Testing Data
(Peptide-+)
anti-Human TNFRSF6B Antibody | anti-TNFRSF6B antibody
TNFRSF6B Antibody
Gene Names
TNFRSF6B; M68; TR6; DCR3; M68E; DJ583P15.1.1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
TNFRSF6B; TNFRSF6B Antibody; Tumor necrosis factor receptor superfamily member 6B; Decoy receptor for Fas ligand; Decoy receptor 3; DcR3; M68; DCR3; TR6; anti-TNFRSF6B antibody
Reactivity
Human
Specificity
TNFRSF6B antibody detects endogenous levels of total TNFRSF6B protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
300
Applicable Applications for anti-TNFRSF6B antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human TNFRSF6B.
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
(Peptide-+)
Testing Data
(Peptide-+)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using TNFRSF6B antibody. Western blot analysis of extracts from HepG2 cells, using TNFRSF6B antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using TNFRSF6B antibody. Western blot analysis of extracts from HepG2 cells, using TNFRSF6B antibody.)
Immunofluorescence (IF)
(Peptide-+ Immunofluorescence analysis of HepG2 cells, using TNFRSF6B antibody.)
Immunofluorescence (IF)
(Peptide-+ Immunofluorescence analysis of HepG2 cells, using TNFRSF6B antibody.)
Product Categories/Family for anti-TNFRSF6B antibody
References
Pitti R.M., Nature 396:699-703(1998). Yu K.-Y., J. Biol. Chem. 274:13733-13736(1999). Bai C., Proc. Natl. Acad. Sci. U.S.A. 97:1230-1235(2000).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32,680 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 6B
NCBI Official Synonym Full Names
TNF receptor superfamily member 6b
NCBI Official Symbol
TNFRSF6B
NCBI Official Synonym Symbols
M68; TR6; DCR3; M68E; DJ583P15.1.1
NCBI Protein Information
tumor necrosis factor receptor superfamily member 6B
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 6B
Protein Family
UniProt Gene Name
TNFRSF6B
UniProt Synonym Gene Names
DCR3; TR6; DcR3
NCBI Description
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]
Uniprot Description
Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis.
Research Articles on TNFRSF6B
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Product Notes
The TNFRSF6B tnfrsf6b (Catalog #AAA852455) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The TNFRSF6B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TNFRSF6B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000. Researchers should empirically determine the suitability of the TNFRSF6B tnfrsf6b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNFRSF6B, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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