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Testing Data #2 (Western blot analysis of extracts from HeLa cells and HuvEc cells, using STK10 antibody.)

anti-Human STK10 Antibody | anti-STK10 antibody

STK10 Antibody

Gene Names
STK10; LOK; PRO2729
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
STK10; STK10 Antibody; kinase GEK2; LOK; Lymphocyte-oriented kinase; Serine/threonine protein kinase 10; anti-STK10 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
STK10 antibody detects endogenous levels of total STK10 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
968
Applicable Applications for anti-STK10 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human STK10.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data #2

(Western blot analysis of extracts from HeLa cells and HuvEc cells, using STK10 antibody.)

Testing Data #2 (Western blot analysis of extracts from HeLa cells and HuvEc cells, using STK10 antibody.)
References
Kuramochi S., Immunogenetics 49:369-375(1999). Ota T., Nat. Genet. 36:40-45(2004). Schmutz J., Nature 431:268-274(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
112,135 Da
NCBI Official Full Name
serine/threonine-protein kinase 10
NCBI Official Synonym Full Names
serine/threonine kinase 10
NCBI Official Symbol
STK10
NCBI Official Synonym Symbols
LOK; PRO2729
NCBI Protein Information
serine/threonine-protein kinase 10
UniProt Protein Name
Serine/threonine-protein kinase 10
UniProt Gene Name
STK10
UniProt Synonym Gene Names
LOK

NCBI Description

This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008]

Uniprot Description

Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.

Research Articles on STK10

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Product Notes

The STK10 stk10 (Catalog #AAA853618) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The STK10 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STK10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:20000. Researchers should empirically determine the suitability of the STK10 stk10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STK10, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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