anti-Human POLDIP3 Antibody | anti-POLDIP3 antibody

POLDIP3 Antibody

Cat. Num. AAA8515008

• Gene Names: POLDIP3; SKAR; PDIP3; PDIP46
• Reactivity: Human
• Applications: Western Blot
• Purity: Immunogen affinity purified
• Synonyms: POLDIP3; POLDIP3 Antibody; 46 kDa DNA polymerase delta interaction protein; KIAA1649; p46; PDIP3; PDIP46; PDP3; Polymerase delta interacting protein 3; anti-POLDIP3 antibody

• Reactivity: Human
• Specificity: POLDIP3 Antibody detects endogenous levels of total POLDIP3
• Purity/Purification: Immunogen affinity purified
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 421

• Applicable Applications for anti-POLDIP3 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthesized peptide
• Preparation and Storage: Store at-20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts from RAW264.7 cells, using POLDIP3 antibody.)

NCBI and Uniprot Product Information

• NCBI GI #: 29837655
• NCBI GeneID: 84271
• NCBI Accession #: NP_115687.2
• NCBI GenBank Nucleotide #: NM_032311.4
• UniProt Accession #: Q9BY77; Q009A7; Q5H972; Q6PGN6; Q7Z6Z0; Q9NSP5; Q9NSP6; A8K6F8; A8K6V9
• Molecular Weight: 46 KD
• NCBI Official Full Name: polymerase delta-interacting protein 3 isoform 1
• NCBI Official Synonym Full Names: DNA polymerase delta interacting protein 3
• NCBI Official Symbol: POLDIP3
• NCBI Official Synonym Symbols: SKAR; PDIP3; PDIP46
• NCBI Protein Information: polymerase delta-interacting protein 3
• UniProt Protein Name: Polymerase delta-interacting protein 3
• Protein Family: Polymerase delta-interacting protein
• UniProt Gene Name: POLDIP3
• UniProt Synonym Gene Names: KIAA1649; PDIP46; p46; SKAR

NCBI Description

This gene encodes an RRM (RNA recognition motif)-containing protein that participates in the regulation of translation by recruiting ribosomal protein S6 kinase beta-1 to mRNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex.