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Western Blot (WB) (Western blot analysis of extracts from COLO205 cells, using ORCTL-2 antibody.)

anti-Human ORCTL-2 Antibody | anti-ORCTL-2 antibody

ORCTL-2 Antibody

Gene Names
SLC22A18; HET; ITM; BWR1A; IMPT1; TSSC5; ORCTL2; BWSCR1A; SLC22A1L; p45-BWR1A
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
ORCTL-2; ORCTL-2 Antibody; Solute carrier family 22 member 18; Organic cation transporter-like protein 2; Imprinted multi-membrane spanning polyspecific transporter-related protein 1; Efflux transporter-like protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein; Tumor-suppressing STF cDNA 5 protein; Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein; p45-Beckwith-Wiedemann region 1 A; p45-BWR1A; Solute carrier family 22 member 1-like; SLC22A18; BWR1A; BWSCR1A; HET; IMPT1; ITM; ORCTL2; SLC22A1L; TSSC5v; anti-ORCTL-2 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
ORCTL-2 antibody detects endogenous levels of total ORCTL-2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
509
Applicable Applications for anti-ORCTL-2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:5000
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human ORCTL-2.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from COLO205 cells, using ORCTL-2 antibody.)

Western Blot (WB) (Western blot analysis of extracts from COLO205 cells, using ORCTL-2 antibody.)
References
Lee M.P., Cancer Res. 58:4155-4159(1998). Morisaki H., DNA Res. 5:235-240(1998). Cooper P.R., Genomics 49:38-51(1998).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,846 Da
NCBI Official Full Name
solute carrier family 22 member 18 isoform a
NCBI Official Synonym Full Names
solute carrier family 22 member 18
NCBI Official Symbol
SLC22A18
NCBI Official Synonym Symbols
HET; ITM; BWR1A; IMPT1; TSSC5; ORCTL2; BWSCR1A; SLC22A1L; p45-BWR1A
NCBI Protein Information
solute carrier family 22 member 18
UniProt Protein Name
Solute carrier family 22 member 18
UniProt Gene Name
SLC22A18
UniProt Synonym Gene Names
BWR1A; BWSCR1A; HET; IMPT1; ITM; ORCTL2; SLC22A1L; TSSC5; ORCTL-2; p45-BWR1A

NCBI Description

This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2015]

Uniprot Description

May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney.

Research Articles on ORCTL-2

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Product Notes

The ORCTL-2 slc22a18 (Catalog #AAA851711) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The ORCTL-2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ORCTL-2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:5000. Researchers should empirically determine the suitability of the ORCTL-2 slc22a18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ORCTL-2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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