Testing Data
anti-Human MRGX1 Antibody | anti-MRGX1 antibody
MRGX1 Antibody
Gene Names
MRGPRX1; GPCR; MGRG2; MRGX1; SNSR4
Reactivity
Human
Applications
Western Blot, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
MRGX1; MRGX1 Antibody; Mas-related G-protein coupled receptor member X1; Sensory neuron-specific G-protein coupled receptor 3/4; MRGPRX1; SNSR3; SNSR4; anti-MRGX1 antibody
Reactivity
Human
Specificity
MRGX1 antibody detects endogenous levels of total MRGX1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
322
Applicable Applications for anti-MRGX1 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:1000
IF: 1:100~1:500
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human MRGX1.
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
Testing Data
Western Blot (WB)
(Peptide-+ Western blot analysis of extracts from MCF-7 cells, using MRGX1 antibody. Immunofluorescence analysis of HepG2 cells, using MRGX1 antibody.)
Western Blot (WB)
(Peptide-+ Western blot analysis of extracts from MCF-7 cells, using MRGX1 antibody. Immunofluorescence analysis of HepG2 cells, using MRGX1 antibody.)
Product Categories/Family for anti-MRGX1 antibody
References
Dong X., Cell 106:619-632(2001). Lembo P.M.C., Nat. Neurosci. 5:201-209(2002). Takeda S., FEBS Lett. 520:97-101(2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,250 Da
NCBI Official Full Name
mas-related G-protein coupled receptor member X1
NCBI Official Synonym Full Names
MAS related GPR family member X1
NCBI Official Symbol
MRGPRX1
NCBI Official Synonym Symbols
GPCR; MGRG2; MRGX1; SNSR4
NCBI Protein Information
mas-related G-protein coupled receptor member X1
UniProt Protein Name
Mas-related G-protein coupled receptor member X1
UniProt Gene Name
MRGPRX1
UniProt Synonym Gene Names
MRGX1; SNSR3; SNSR4
Uniprot Description
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.
Research Articles on MRGX1
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Product Notes
The MRGX1 mrgprx1 (Catalog #AAA856622) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The MRGX1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MRGX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:1000. Researchers should empirically determine the suitability of the MRGX1 mrgprx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRGX1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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