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Testing Data (HNF4A antibody at 1/2000 dilution interacts with recombinant HNF4A protein with a DsbA tag. Predicted band size: 53KDa. Observed band size: 53KDa.)

anti-Human HNF4A Antibody | anti-HNF4A antibody

HNF4A Antibody

Gene Names
HNF4A; TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; HNF4alpha
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Protein G-Sepharose affinity purified
Synonyms
HNF4A; HNF4A Antibody; Mouse monoclonal IgG to HNF4A; anti-HNF4A antibody
Ordering
For Research Use Only!
Reactivity
Human
Purity/Purification
Protein G-Sepharose affinity purified
Form/Format
Liquid
Sequence Length
504
Applicable Applications for anti-HNF4A antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:5000-1:20000
WB: 1:100-1:2000
Immunogen
Recombinant fragment of Human HNF4A (C-terminus).
Preservative
0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
Cellular Localization
Nucleus
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.

Testing Data

(HNF4A antibody at 1/2000 dilution interacts with recombinant HNF4A protein with a DsbA tag. Predicted band size: 53KDa. Observed band size: 53KDa.)

Testing Data (HNF4A antibody at 1/2000 dilution interacts with recombinant HNF4A protein with a DsbA tag. Predicted band size: 53KDa. Observed band size: 53KDa.)
Related Product Information for anti-HNF4A antibody
HNF4 (Hepatocyte Nuclear Factor 4) is a nuclear receptor protein belonging to the steroid hormone receptor superfamily. HNF4 is commonly expressed in the liver and plays a critical role in liver development by establishing and maintaining hepatocyte differentiation. In human, two isoforms of HNF4 exists, alpha and gamma. HNF4 alpha is transcriptionally controlled transcription factor, which binds to DNA sites required for the transcription of alpha 1-antitrypsin, Apo CIII, transthyretin genes, and HNF1 alpha.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
43,988 Da
NCBI Official Full Name
hepatocyte nuclear factor 4 alpha (HNF4alpha4)
NCBI Official Synonym Full Names
hepatocyte nuclear factor 4 alpha
NCBI Official Symbol
HNF4A
NCBI Official Synonym Symbols
TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; HNF4alpha
NCBI Protein Information
hepatocyte nuclear factor 4-alpha
UniProt Protein Name
Hepatocyte nuclear factor 4-alpha
Protein Family
UniProt Gene Name
HNF4A
UniProt Synonym Gene Names
HNF4; NR2A1; TCF14; HNF-4-alpha; TCF-14

NCBI Description

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]

Uniprot Description

Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1-antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1-alpha. May be essential for development of the liver, kidney and intestine.

Research Articles on HNF4A

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Product Notes

The HNF4A hnf4a (Catalog #AAA850306) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The HNF4A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HNF4A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:5000-1:20000 WB: 1:100-1:2000. Researchers should empirically determine the suitability of the HNF4A hnf4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HNF4A, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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