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Testing Data (Peptide-+)

anti-Human ENTK Antibody | anti-ENTK antibody

ENTK Antibody

Gene Names
TMPRSS15; ENTK; PRSS7
Reactivity
Human
Applications
Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
ENTK; ENTK Antibody; Enteropeptidase; EC 3.4.21.9; Enterokinase; Serine protease 7; Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain; PRSS7; anti-ENTK antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
ENTK antibody detects endogenous levels of total ENTK protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1019
Applicable Applications for anti-ENTK antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
IF: 1:100-1:500
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human ENTK.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

(Peptide-+)

Testing Data (Peptide-+)

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ENTK antibody. Immunofluorescence analysis of HepG2 cells, using ENTK antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ENTK antibody. Immunofluorescence analysis of HepG2 cells, using ENTK antibody.)
References
Kitamoto Y., Biochemistry 34:4562-4568(1995). Holzinger A., Am. J. Hum. Genet. 70:20-25(2002). Hattori M., Nature 405:311-319(2000).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
112,935 Da
NCBI Official Full Name
enteropeptidase
NCBI Official Synonym Full Names
transmembrane serine protease 15
NCBI Official Symbol
TMPRSS15
NCBI Official Synonym Symbols
ENTK; PRSS7
NCBI Protein Information
enteropeptidase
UniProt Protein Name
Enteropeptidase
UniProt Gene Name
TMPRSS15
UniProt Synonym Gene Names
ENTK; PRSS7

NCBI Description

This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive. [provided by RefSeq, Jul 2008]

Uniprot Description

Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.

Research Articles on ENTK

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Product Notes

The ENTK tmprss15 (Catalog #AAA859221) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The ENTK Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ENTK can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). IHC: 1:50-1:100 IF: 1:100-1:500 ELISA: 1:20000. Researchers should empirically determine the suitability of the ENTK tmprss15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ENTK, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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