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Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DGKZ antibody.)

anti-Human DGKZ Antibody | anti-DGKZ antibody

DGKZ Antibody

Gene Names
DGKZ; DAGK5; DAGK6; DGK-ZETA; hDGKzeta
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
DGKZ; DGKZ Antibody; EC 2.7.1.107; Diglyceride kinase zeta; DGK-zeta; DAG kinase zeta; anti-DGKZ antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
DGKZ antibody detects endogenous levels of total DGKZ protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1117
Applicable Applications for anti-DGKZ antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human DGKZ.
Preparation and Storage
Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DGKZ antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DGKZ antibody.)
References
Bunting M., J. Biol. Chem. 271:10230-10236(1996). Ding L., Proc. Natl. Acad. Sci. U.S.A. 94:5519-5524(1997). Topham M.K., Nature 394:697-700(1998).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
104,296 Da
NCBI Official Full Name
diacylglycerol kinase zeta isoform 4
NCBI Official Synonym Full Names
diacylglycerol kinase zeta
NCBI Official Symbol
DGKZ
NCBI Official Synonym Symbols
DAGK5; DAGK6; DGK-ZETA; hDGKzeta
NCBI Protein Information
diacylglycerol kinase zeta
UniProt Protein Name
Diacylglycerol kinase zeta
Protein Family
UniProt Gene Name
DGKZ
UniProt Synonym Gene Names
DAGK6; DAG kinase zeta; DGK-zeta

NCBI Description

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010]

Uniprot Description

Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 activity.

Research Articles on DGKZ

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Product Notes

The DGKZ dgkz (Catalog #AAA853520) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The DGKZ Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DGKZ can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:20000. Researchers should empirically determine the suitability of the DGKZ dgkz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DGKZ, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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