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Western Blot (WB) (Western blot analysis of extracts fromHepG2 cells and Jurkat cells, using CLDN19 antibody.)

anti-Human CLDN19 Antibody | anti-CLDN19 antibody

CLDN19 Antibody

Gene Names
CLDN19; HOMG5
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CLDN19; CLDN19 Antibody; claudin-19; CLD19; anti-CLDN19 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
CLDN19 antibody detects endogenous levels of total CLDN19 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
211
Applicable Applications for anti-CLDN19 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CLDN19.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts fromHepG2 cells and Jurkat cells, using CLDN19 antibody.)

Western Blot (WB) (Western blot analysis of extracts fromHepG2 cells and Jurkat cells, using CLDN19 antibody.)
References
Ota T., Nat. Genet. 36:40-45(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004). Konrad M., Am. J. Hum. Genet. 79:949-957(2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,721 Da
NCBI Official Full Name
claudin-19 isoform b
NCBI Official Synonym Full Names
claudin 19
NCBI Official Symbol
CLDN19
NCBI Official Synonym Symbols
HOMG5
NCBI Protein Information
claudin-19
UniProt Protein Name
Claudin-19
Protein Family
UniProt Gene Name
CLDN19

NCBI Description

The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]

Uniprot Description

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Research Articles on CLDN19

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Product Notes

The CLDN19 cldn19 (Catalog #AAA855147) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CLDN19 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLDN19 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the CLDN19 cldn19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLDN19, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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