Human Phospholipase A2 Activating Protein (PLAA) Antibody Pair Kit | PLAA antibody pair kit

Human Phospholipase A2 Activating Protein (PLAA) Antibody Pair Kit (with Standard)

Gene Names

PLAA; DOA1; PLAP; PLA2P; NDMSBA

Reactivity

Human

Applications

ELISA, ELISA

Synonyms

Phospholipase A2 Activating Protein (PLAA); Human Phospholipase A2 Activating Protein (PLAA) Antibody Pair Kit (with Standard); PLAP; PLA2P; PLA2-P; DOA1; PLAA antibody pair kit

Ordering
Cat. Num. AAA2099151 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Human

Applicable Applications for PLAA antibody pair kit

ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex

Samples

Serum, Plasma, Tissue Homogenates and Other Biological Fluids

Detection Range

0.625-40ng/mL

Standard

Recombinant PLAA (Lyophilized, 1 vial-10ug)

Capture Antibody

Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)

Detection Antibody

Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)

Producte Usage

Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.

Antibody Support Pack

Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685

Product Categories/Family for PLAA antibody pair kit

Enzyme & Kinase; Metabolic pathway; Infection immunity

NCBI and Uniprot Product Information

NCBI GI #

5326866

NCBI GeneID

9373

Molecular Weight

87,157 Da

NCBI Official Full Name

phospholipase A2 activating protein

NCBI Official Synonym Full Names

phospholipase A2 activating protein

NCBI Official Symbol

PLAA

NCBI Official Synonym Symbols

DOA1; PLAP; PLA2P; NDMSBA

NCBI Protein Information

phospholipase A-2-activating protein

UniProt Protein Name

Phospholipase A-2-activating protein

Protein Family

Phospholipase A-2-activating protein

UniProt Gene Name

PLAA

UniProt Synonym Gene Names

PLAP; PLA2P; PLAP

Uniprot Description

Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (PubMed:27753622). Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling (). May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622). Plays a role in cerebellar Purkinje cell development (). Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis (PubMed:18291623, PubMed:28007986).

Research Articles on PLAA

1. In both human and mouse, hypomorphic mutations in the ubiquitin adaptor protein PLAA cause an infantile-lethal neurodysfunction syndrome with seizures.

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Product Notes

The Human PLAA plaa (Catalog #AAA2099151) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2099151 Antibody Pair Kit recognizes Human PLAA. AAA Biotech's Phospholipase A2 Activating Protein (PLAA) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the PLAA plaa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Phospholipase A2 Activating Protein (PLAA), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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