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Human Collagen Type VIII Alpha 2 (COL8a2) Antibody Pair Kit | COL8a2 antibody pair kit

Human Collagen Type VIII Alpha 2 (COL8a2) Antibody Pair Kit (with Standard)

Gene Names
COL8A2; FECD; PPCD; FECD1; PPCD2
Reactivity
Human
Applications
ELISA, ELISA
Synonyms
Collagen Type VIII Alpha 2 (COL8a2); Human Collagen Type VIII Alpha 2 (COL8a2) Antibody Pair Kit (with Standard); COL8-A2; FECD; PPCD; PPCD2; Collagen Alpha-2(VIII)chain; Endothelial collagen; COL8a2 antibody pair kit
Ordering
For Research Use Only!
Reactivity
Human
Applicable Applications for COL8a2 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
Samples
Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids
Detection Range
31.2-2000ng/mL
Standard
Recombinant COL8a2 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
Product Categories/Family for COL8a2 antibody pair kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
67,244 Da
NCBI Official Full Name
collagen type VIII alpha 2, partial
NCBI Official Synonym Full Names
collagen type VIII alpha 2 chain
NCBI Official Symbol
COL8A2
NCBI Official Synonym Symbols
FECD; PPCD; FECD1; PPCD2
NCBI Protein Information
collagen alpha-2(VIII) chain
UniProt Protein Name
Collagen alpha-2(VIII) chain
UniProt Gene Name
COL8A2

NCBI Description

This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

Uniprot Description

Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis ().

Research Articles on COL8a2

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Product Notes

The Human COL8a2 col8a2 (Catalog #AAA2102320) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2102320 Antibody Pair Kit recognizes Human COL8a2. AAA Biotech's Collagen Type VIII Alpha 2 (COL8a2) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the COL8a2 col8a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Collagen Type VIII Alpha 2 (COL8a2), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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