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BMP11 active protein

BMP11 protein

Purity
> 98% pure
BMP11 protein was purified using a a proprietary chromatographic technique.
Synonyms
BMP11; BMP11 protein; BMP 11 protein; Growth/Differentiation Factor-11 protein; BMP-11 protein; GDF11 protein; GDF-11 protein; BMP 11; BMP-11; Bone morphogenetic protein 11 protein; GDF 11 protein; BMP11 active protein
Ordering
For Research Use Only!
Host
Human
Purity/Purification
> 98% pure
BMP11 protein was purified using a a proprietary chromatographic technique.
Form/Format
Supplied in lyophilized form from 10 mM Sodium Citrate, pH 3.5
Sequence Length
407
Protein Type
Recombinant
Biological Significance
BMPs belong to the TGF beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues.
Bioactivity
The ED50 is in the range of 0.04-4 ug/ml
Endotoxin Levels
<0.1 ng/ug
Expression System
E Coli
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for BMP11 active protein
Purified recombinant Human BMP11 protein
Product Categories/Family for BMP11 active protein

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
32.6 kDa
NCBI Official Full Name
bone morphogenetic protein 11
UniProt Protein Name
Growth/differentiation factor 11
UniProt Gene Name
GDF11
UniProt Synonym Gene Names
BMP11; GDF-11; BMP-11
UniProt Entry Name
GDF11_HUMAN

Uniprot Description

GDF11: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: nervous system development; cell maturation; palate development; regulation of apoptosis; negative regulation of cell proliferation; negative regulation of cell differentiation; camera-type eye morphogenesis; spinal cord anterior/posterior patterning; ureteric bud development; regulation of MAPKKK cascade; pancreas development; mesoderm development; cell development; skeletal development; metanephros development; growth

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Product Notes

The BMP11 gdf11 (Catalog #AAA5304383) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BMP11, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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