Serine protease HTRA2, mitochondrial (HtrA2) Recombinant Protein | DsecGM25850 recombinant protein
Recombinant Drosophila sechellia Serine protease HTRA2, mitochondrial (HtrA2)
NCBI and Uniprot Product Information
Uniprot Description
Function: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Can antagonize antiapoptotic activity of th by directly inducing the degradation of th
By similarity. UniProtKB Q9VFJ3
Catalytic activity: Cleavage of non-polar aliphatic amino-acids at the P1 position, with a preference for Val, Ile and Met. At the P2 and P3 positions, Arg is selected most strongly with a secondary preference for other hydrophilic residues.
Subunit structure: Interacts with th/DIAP1 (via BIR 2 domain)
By similarity. UniProtKB Q9VFJ3
Subcellular location: Mitochondrion intermembrane space; Single-pass membrane protein
By similarity. Mitochondrion membrane; Single-pass membrane protein
Potential.
Sequence similarities: Belongs to the peptidase S1B family.Contains 1 PDZ (DHR) domain.
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Product Notes
The DsecGM25850 htra2 (Catalog #AAA1135701) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 75-422. The amino acid sequence is listed below: AAVSAAIIQR EDLTPTIAAS KMTGRRRDFN FIADVVAGCA DSVVYIEIKD TRHFDYFSGQ PITASNGSGF IIEQNGLILT NAHVVINKPH TMVQVRLSDG RTFPATIEDV DQTSDLATLR IQVNNLSVMR LGKSSTLRSG EWVVALGSPL ALSNTVTAGV ISSTQRASQE LGLRNRDINY LQTDAAITFG NSGGPLVNLD GEAIGVNSMK VTAGISFAIP IDYVKVFLER AAEKRKKGSA YKTGYPVKRY MGITMLTLTP DILFELKSRS QNMPSNLTHG VLVWKVIVGS PAHSGGLQPG DIVTHINKKE IKNSSDVYDA LADNSKTLDI VILRGVKQMH VTITPEDP. It is sometimes possible for the material contained within the vial of "Serine protease HTRA2, mitochondrial (HtrA2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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