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Western Blot (WB) (Western blot analysis of Kv3.1 expression in HepG2 (A), rat brain (B) whole cell lysates.)

Rabbit Kv3.1 Polyclonal Antibody | anti-KCNC1 antibody

Anti-Kv3.1 Antibody

Gene Names
KCNC1; KV4; NGK2; KV3.1
Reactivity
Human, Mouse, Rat, Bovine, Rabbit
Applications
Western Blot
Purity
The antibody was purified by immunogen affinity chromatography.
Synonyms
Kv3.1; Polyclonal Antibody; Anti-Kv3.1 Antibody; Potassium voltage-gated channel subfamily C member 1; NGK2; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4; anti-KCNC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine, Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of Kv3.1 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
585
Applicable Applications for anti-KCNC1 antibody
Western Blot (WB)
Application Notes
WB (1/500 - 1/1000)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Kv3.1. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of Kv3.1 expression in HepG2 (A), rat brain (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of Kv3.1 expression in HepG2 (A), rat brain (B) whole cell lysates.)

Immunohistochemistry (IHC)

()

Immunohistochemistry (IHC) ()
Related Product Information for anti-KCNC1 antibody
Rabbit polyclonal antibody to Kv3.1

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,928 Da
NCBI Official Full Name
potassium voltage-gated channel subfamily C member 1 isoform A
NCBI Official Synonym Full Names
potassium voltage-gated channel, Shaw-related subfamily, member 1
NCBI Official Symbol
KCNC1
NCBI Official Synonym Symbols
KV4; NGK2; KV3.1
NCBI Protein Information
potassium voltage-gated channel subfamily C member 1; voltage-gated potassium channel subunit Kv4; voltage-gated potassium channel protein KV3.1
UniProt Protein Name
Potassium voltage-gated channel subfamily C member 1
UniProt Gene Name
Kcnc1
UniProt Entry Name
KCNC1_RAT

NCBI Description

This gene encodes a member of a family of integral membrane proteins that mediate the voltage-dependent potassium ion permeability of excitable membranes. Alternative splicing is thought to result in two transcript variants encoding isoforms that differ at their C-termini. These isoforms have had conflicting names in the literature: the longer isoform has been called both "b" and "alpha", while the shorter isoform has been called both "a" and "beta" (PMIDs 1432046, 12091563). [provided by RefSeq, Oct 2014]

Uniprot Description

Kv3.1: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.1/KCNC1 sub-subfamily.

Protein type: Membrane protein, multi-pass; Channel, potassium; Membrane protein, integral

Cellular Component: voltage-gated potassium channel complex; cell surface; membrane; cell soma; dendrite; integral to membrane; axolemma

Molecular Function: voltage-gated potassium channel activity; potassium channel activity; kinesin binding; delayed rectifier potassium channel activity; ion channel activity; voltage-gated ion channel activity

Biological Process: transport; ion transport; transmembrane transport; protein homooligomerization; potassium ion transport

Research Articles on KCNC1

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Product Notes

The KCNC1 kcnc1 (Catalog #AAA821637) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Kv3.1 Antibody reacts with Human, Mouse, Rat, Bovine, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's Kv3.1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the KCNC1 kcnc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kv3.1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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