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HTLV-1 p24 Core Recombinant Protein

Recombinant HTLV-1 p24 Core

Applications
ELISA, Western Blot
Purity
HTLV-1 p24 protein is >95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC.
HTLV-1 p24 was purified by proprietary chromatographic technique.
Synonyms
HTLV-1 p24 Core; Recombinant HTLV-1 p24 Core; HTLV-1 p24 core; HTLV-1 p24 Core Recombinant; HTLV-1 p24c; HTLV-1 p24 Core recombinant protein
Ordering
For Research Use Only!
Specificity
Immunoreactive with all sera of HTLV-1 infected individuals.
Purity/Purification
HTLV-1 p24 protein is >95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC.
HTLV-1 p24 was purified by proprietary chromatographic technique.
Form/Format
50mM NaPO4 pH 6.0, containing 1mM DTT & 1mM EDTA.
Applicable Applications for HTLV-1 p24 Core recombinant protein
ELISA (EIA), Western Blot (WB)
Application Notes
HTLV-1 p24 antigen can be used for ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.
Preparation and Storage
HTLV-1 p24 although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.
Related Product Information for HTLV-1 p24 Core recombinant protein
Description: The E Coli derived recombinant protein contains the full-length sequence of HTLV-I p24, spanning all of p24.The protein contains 214 amino acids having an Mw of 24kDa.

Introduction: Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).
Product Categories/Family for HTLV-1 p24 Core recombinant protein

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Product Notes

The HTLV-1 p24 Core (Catalog #AAA142596) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's HTLV-1 p24 Core can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). HTLV-1 p24 antigen can be used for ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems. Researchers should empirically determine the suitability of the HTLV-1 p24 Core for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HTLV-1 p24 Core, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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