17-beta-hydroxysteroid dehydrogenase 14 Recombinant Protein | DHB14 recombinant protein
Recombinant Human 17-beta-hydroxysteroid dehydrogenase 14
NCBI and Uniprot Product Information
NCBI Description
17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]
Uniprot Description
HSD17B14: Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein type: EC 1.1.1.-; Oxidoreductase
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: cytosol
Molecular Function: estradiol 17-beta-dehydrogenase activity; identical protein binding; protein binding; testosterone 17-beta-dehydrogenase (NADP+) activity
Biological Process: estrogen biosynthetic process; steroid catabolic process
Research Articles on DHB14
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Product Notes
The DHB14 hsd17b14 (Catalog #AAA9421363) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length, 1-270aa. The Recombinant Human 17-beta-hydroxysteroid dehydrogenase 14 reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "17-beta-hydroxysteroid dehydrogenase 14, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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