Hematopoietic Prostaglandin D Synthase/HPGDS/GSTS Recombinant Protein | HPGDS/GSTS recombinant protein
Recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS/GSTS Protein
Gene Names
HPGDS; GSTS; PGD2; PGDS; GSTS1; GSTS1-1
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Hematopoietic Prostaglandin D Synthase/HPGDS/GSTS; Recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS/GSTS Protein; Hematopoietic Prostaglandin D Synthase; H-PGDS; GST Class-Sigma; Glutathione S-Transferase; Glutathione-Dependent PGD Synthase; Glutathione-Requiring Prostaglandin D Synthase; Prostaglandin-H2 D-Isomerase; HPGDS; GSTS; PGDS; PTGDS2; HPGDS/GSTS recombinant protein
Host
E Coli
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 mum filtered solution of 20mM Tris, 200mM NaCl, pH 7.0.
Sequence Positions
Met1-Leu199
Sequence Length
199
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Related Product Information for HPGDS/GSTS recombinant protein
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 23.6 kDa
Actual Protein Molecular Mass: 26 kDa
Actual Protein Molecular Mass: 26 kDa
NCBI Official Full Name
hematopoietic prostaglandin D synthase
NCBI Official Synonym Full Names
hematopoietic prostaglandin D synthase
NCBI Official Symbol
HPGDS
NCBI Official Synonym Symbols
GSTS; PGD2; PGDS; GSTS1; GSTS1-1
NCBI Protein Information
hematopoietic prostaglandin D synthase
UniProt Protein Name
Hematopoietic prostaglandin D synthase
UniProt Gene Name
HPGDS
UniProt Synonym Gene Names
GSTS; PGDS; PTGDS2; H-PGDS
NCBI Description
Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. [provided by RefSeq, Jul 2008]
Uniprot Description
Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
Research Articles on HPGDS/GSTS
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Product Notes
The HPGDS/GSTS hpgds (Catalog #AAA2552754) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1-Leu199. It is sometimes possible for the material contained within the vial of "Hematopoietic Prostaglandin D Synthase/HPGDS/GSTS, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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