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hop recombinant protein

HOP, Recombinant, Human (HSP70 HSP90 Organizing Protein)

Applications
Western Blot
Purity
Highly Purified
~90%
Synonyms
HOP; Recombinant; Human (HSP70 HSP90 Organizing Protein); hop recombinant protein
Ordering
For Research Use Only!
Host
Human cDNA, expressed in E Coli
Purity/Purification
Highly Purified
~90%
Form/Format
Supplied as a liquid in 20mM HEPES buffer p7.2, 80mM sodium chloride in10% glyercol.
Applicable Applications for hop recombinant protein
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for hop recombinant protein
Hop (Hsp70/Hsp90 Organizing Protein), or Stress-induced Phosphoprotein 1 (STI1) as it is also known, is a 60kDa protein that belongs to the large group of co-chaperones which regulate and assist the major chaperones. It is located in diverse cellular regions and can move between the cytoplasm and the nucleus. It functions to reversibly link together the protein chaperones Hsp70 and Hsp90. HOP contains three tetratricopeptide repeat (TPR) domains, TPR1, TPR2a and TPR2b. Hsp70 binding has been localized to TRP1 and sp90 binding have been localized to TPR2a (1). It has also been found to modulate the chaperone activities of the linked proteins and possible interacts with other chaperones and proteins. It has also been found to participate in other complexes besides the Hsp70/Hsp90 one (2). HOP is closely related to human 63kDa protein that is sensitive to simian virus SV40 transformation, and is related to the yeast heat-shock- responsive STI1 gene product (3, 4).
Product Categories/Family for hop recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
90kD
NCBI Official Full Name
Hop
NCBI Official Symbol
hop
NCBI Protein Information
Hop; halorhodopsin
UniProt Protein Name
Halorhodopsin
Protein Family
UniProt Gene Name
hop
UniProt Synonym Gene Names
HR
UniProt Entry Name
BACH_HALSA

Uniprot Description

Function: Halorhodopsin is a light-driven chloride pump.

Subunit structure: Homotrimer.

Subcellular location: Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the archaeal/bacterial/fungal opsin family.

Biophysicochemical propertiesAbsorption:Abs(max)=~568 nmIn the presence of anions, the maximum absorption shifts to about 578 nm.

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Product Notes

The hop hop (Catalog #AAA636747) is a Recombinant Protein produced from Human cDNA, expressed in E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's HOP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the hop hop for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HOP, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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