Typical Testing Data/Standard Curve (for reference only)
Mouse Heterogeneous nuclear ribonucleoprotein K ELISA Kit | Hnrnpk elisa kit
Mouse Heterogeneous nuclear ribonucleoprotein K ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, and is a poly-cytosine binding protein (PCBP). It is found in multiple subcellular compartments including the nucleus, cytoplasm and mitochondria. This gene product is thought to interact with RNA, DNA, and protein, and is involved in multiple cellular processes, including transcription, chromatin remodeling, DNA damage response, signal transduction, mRNA splicing, export, and translation. Multiple transcript variants and protein isoforms exist, with some isoforms containing a unique C-terminus. There are four pseudogenes of this gene, found on chromosomes 2, 3, 7 and 13. [provided by RefSeq, Aug 2014]
Uniprot Description
hnRNP K: a heterogeneous nuclear ribonucleoprotein (hnRNP). One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Two alternatively spliced isoforms have been described.
Protein type: RNA splicing; Spliceosome; RNA-binding
Cellular Component: cell cortex; cell junction; cell projection; cytoplasm; cytosol; dendritic spine; focal adhesion; membrane; mitochondrion; nerve terminal; nuclear chromatin; nucleus; postsynaptic density; ribonucleoprotein complex; spliceosome
Molecular Function: actinin binding; ATPase binding; DNA binding; double-stranded DNA binding; heat shock protein binding; lamin binding; mRNA 3'-UTR binding; nucleic acid binding; pre-mRNA 3'-splice site binding; protein binding; protein domain specific binding; ribonucleoprotein binding; RNA binding; single-stranded DNA binding; transcription factor binding
Biological Process: cellular response to insulin stimulus; cerebral cortex development; mRNA processing; negative regulation of apoptosis; negative regulation of nuclear mRNA splicing, via spliceosome; negative regulation of protein binding; negative regulation of transcription from RNA polymerase II promoter; ovarian follicle development; positive regulation of low-density lipoprotein receptor biosynthetic process; positive regulation of receptor-mediated endocytosis; positive regulation of RNA splicing; positive regulation of synaptic transmission; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; RNA splicing; transcription from RNA polymerase II promoter; transcription, DNA-dependent
Research Articles on Hnrnpk
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Product Notes
The Mouse Hnrnpk hnrnpk (Catalog #AAA2886148) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886148 ELISA Kit recognizes Mouse Hnrnpk. It is sometimes possible for the material contained within the vial of "Heterogeneous nuclear ribonucleoprotein K, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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