Mouse high-mobility group box 1 ELISA Kit | HMGB1 elisa kit
Mouse High mobility group protein B1, HMGB-1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]
Uniprot Description
Function: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.1 PublicationManual assertion based on experiment in:Ref.7
Research Articles on HMGB1
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Product Notes
The Mouse HMGB1 hmgb1 (Catalog #AAA705143) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA705143 ELISA Kit recognizes Mouse HMGB1. It is sometimes possible for the material contained within the vial of "high-mobility group box 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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