Hepatitis B virus Pre-S Recombinant Protein | Pre-S recombinant protein
Hepatitis B virus Pre-S (Pre-S1 + Pre-S2)
Applications
ELISA, Western Blot
Purity
>95% pure (12% PAGE Coomassie blue stain). Proprietary chromatographic technique.
Synonyms
Hepatitis B virus Pre-S; Hepatitis B virus Pre-S (Pre-S1 + Pre-S2); Pre-S recombinant protein
Host
E Coli
Specificity
>95% pure (12% PAGE Coomassie blue stain). Proprietary chromatographic technique.
Purity/Purification
>95% pure (12% PAGE Coomassie blue stain). Proprietary chromatographic technique.
Form/Format
Purified, Liquid. PBS with 1M urea, 0.05% sodium azide
Concentration
0.6mg/ml (04-2015) (varies by lot)
Applicable Applications for Pre-S recombinant protein
ELISA (EIA), Western Blot (WB)
Protein Structure
Whole length Pre-S of HBV subtype adw2 was expressedfrom E Coli containing 174 amino acids, with molecular weight about 25kDa plus with vector sequence and a 6 x his tag linked at its C-terminal.
Preparation and Storage
Upon receipt, store at -20 degree C. Avoid multiple freeze/thaw cycles.
Related Product Information for Pre-S recombinant protein
Hepatitis B virus surface gene encodes small(HBs), middle (MHBs) and large (LHBs) surface protein.These proteins are translated from distinct start codons, butshare a common reading frame and stop codon. HBs has 226amino acids, a major viral envelope component. MHBs hasextra 55 amino acids (Pre-S2) located to its N-terminal of ofHBs, LHBs is with an additional 119 amino acids (Pre-S1).
Pre-S is a region containing Pre-S1 and S2, Pre-S1 plays animportant role in receptor recognition, while Pre-S2 plays arole in translocation of virus into host cell. Clinically, HBVpre-S is associated with HBsAg and HBV DNA copies,indicating active replication of virus, reduction of pre-S isusually associating with decreased HBV DNA copies, itindicates an improved predictor of treatment. Pre-S is also apotential vaccine under development to supplement currentlyused HBsAg vaccine.
Pre-S is a region containing Pre-S1 and S2, Pre-S1 plays animportant role in receptor recognition, while Pre-S2 plays arole in translocation of virus into host cell. Clinically, HBVpre-S is associated with HBsAg and HBV DNA copies,indicating active replication of virus, reduction of pre-S isusually associating with decreased HBV DNA copies, itindicates an improved predictor of treatment. Pre-S is also apotential vaccine under development to supplement currentlyused HBsAg vaccine.
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Product Notes
The Pre-S (Catalog #AAA596058) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Hepatitis B virus Pre-S can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the Pre-S for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hepatitis B virus Pre-S, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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