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Hepatitis B Recombinant Protein

Virus like particle formed by recombinant hepatitis B virus core antigen

Applications
Immunoassay (IA)
Purity
Purified by a proprietary chromatographic technique with 95% purity on 12% SDS-PAGE
Synonyms
Hepatitis B; Virus like particle formed by recombinant hepatitis B virus core antigen; HBV virus like particle formaed by recombinant hepatitis B core antigen; Hepatitis B recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Purified by a proprietary chromatographic technique with 95% purity on 12% SDS-PAGE
Applicable Applications for Hepatitis B recombinant protein
Immunoassay (IA)
Protein Buffer
PBS with 1M urea
Tag
6 x Histidine
Related Product Information for Hepatitis B recombinant protein
The hepatitis B virus is major cause for human liver disease, chronic infection usually causes liver cancer and cirrhosis. The outer viron is covered by a layer derived from endoplasmic reticulum and virus-encoded surface protein. Inside of this layer encloses the viral nucleocapside, i.e. core antigen which contains the viral genome. The capsid consisits of dimmers of a 183-residue protein, which can be divided into a fragment (1-149) responsible for assembling and a basic residue-composed domain responsible for polymerization into particle and RNA packaging, respectively. The core antigen is found on virus particles but disappears early in the course of infection. This antibody is produced during and after an acute HBV infection and is also found in chronic HBV carriers as well as those who have cleared the virus, and usually persists for life. This recombinant core antigen consists of HBV core immunodominant region amino acids 1-183. It was expressed from E Coli, the purified recombinant core antigen can be used for ELISA assay and Western blot for clinical study and research. Some times, virus like particle can be found from over 30% E Coli expressed viral antigen, multiple antigens can aggregate into one large particle, even though with reducing condition, multiplized proteins, such as dimer, trimer is still present on SDS-PAGE. Aggregated virus like particle has strong ability in immunal reaction, they can be used for vaccine study or generate better result in immunoassay for identification.

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Product Notes

The Hepatitis B (Catalog #AAA596063) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Hepatitis B can be used in a range of immunoassay formats including, but not limited to, Immunoassay (IA). Researchers should empirically determine the suitability of the Hepatitis B for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hepatitis B, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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