SDS-Page
(Figure 1. Human CD22, hFc-His Tag on SDS-PAGE under reducing condition.)
CD22 protein
Human CD22 Protein, hFc-His Tag
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Synonyms
CD22; Human CD22 Protein; hFc-His Tag; SIGLEC2; BL-CAM; SIGLEC-2; Siglec2; SIGLEC2FLJ22814; CD22 protein
Host
HEK293 cells
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5 %-12 % trehalose is added as protectants before lyophilization.
Sequence Positions
CD22 (Asp20-Arg687)+hFc (Glu99-Ala330)
Species
Human
Vector and Tag
C-Human Fc and 6xHis tag
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
SDS-Page
(Figure 1. Human CD22, hFc-His Tag on SDS-PAGE under reducing condition.)
SDS-Page
(Figure 1. Human CD22, hFc-His Tag on SDS-PAGE under reducing condition.)
Related Product Information for CD22 protein
B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2/CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2/CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
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Product Notes
The CD22 (Catalog #AAA8575063) is a Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is CD22 (Asp20-Arg687)+hFc (Glu99-Ala330). It is sometimes possible for the material contained within the vial of "CD22, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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