Mouse HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 ELISA Kit | HECW1 elisa kit
Mouse E3 ubiquitin-protein ligase HECW1, HECW1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
HECW1: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
Protein type: Ubiquitin ligase; Ubiquitin conjugating system; EC 6.3.2.-; Ligase; EC 6.3.2.19
Cellular Component: cytoplasm; nucleus
Molecular Function: coenzyme F420-2 alpha-glutamyl ligase activity; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity; ribosomal S6-glutamic acid ligase activity; ubiquitin-protein ligase activity; coenzyme F420-0 gamma-glutamyl ligase activity; ligase activity
Biological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process
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Product Notes
The Mouse HECW1 hecw1 (Catalog #AAA9317522) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317522 ELISA Kit recognizes Mouse HECW1. It is sometimes possible for the material contained within the vial of "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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