Hamster Tyrosine-Protein Kinase Fer (FER) ELISA Kit | FER elisa kit
Hamster Tyrosine-Protein Kinase Fer (FER) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Apr 2015]
Uniprot Description
Fer: a non-receptor tyrosine kinase of the Fer family. Regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. Increased expression associated with prostate cancer proliferation, and antisense blocks soft agar growth.
Protein type: EC 2.7.10.2; Fer family; Kinase, protein; Oncoprotein; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); TK group
Chromosomal Location of Human Ortholog: 5q21.3
Cellular Component: actin cytoskeleton; cell cortex; cell junction; cytoplasm; cytosol; extrinsic component of cytoplasmic side of plasma membrane; lamellipodium; microtubule cytoskeleton; nuclear chromatin; nucleus
Molecular Function: ATP binding; epidermal growth factor receptor binding; lipid binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein phosphatase 1 binding; protein tyrosine kinase activity
Biological Process: actin cytoskeleton reorganization; cell adhesion; cell differentiation; cell proliferation; cell-cell adhesion mediated by cadherin; cellular response to insulin stimulus; cellular response to reactive oxygen species; chemotaxis; cytokine-mediated signaling pathway; diapedesis; Fc-epsilon receptor signaling pathway; innate immune response; insulin receptor signaling pathway via phosphatidylinositol 3-kinase; interleukin-6-mediated signaling pathway; Kit signaling pathway; microtubule cytoskeleton organization; mitotic cell cycle; negative regulation of mast cell activation involved in immune response; peptidyl-tyrosine autophosphorylation; peptidyl-tyrosine phosphorylation; platelet-derived growth factor receptor signaling pathway; positive regulation of actin filament polymerization; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of NF-kappaB transcription factor activity; protein amino acid phosphorylation; protein autophosphorylation; regulation of epidermal growth factor receptor signaling pathway; regulation of fibroblast migration; regulation of lamellipodium assembly; regulation of mast cell degranulation; regulation of protein amino acid phosphorylation; response to lipopolysaccharide; tyrosine phosphorylation of STAT protein
Research Articles on FER
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Product Notes
The Hamster FER fer (Catalog #AAA9908556) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9908556 ELISA Kit recognizes Hamster FER. It is sometimes possible for the material contained within the vial of "Tyrosine-Protein Kinase Fer (FER), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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