Hamster Troponin I Type 1, Slow Skeletal (TNNI1) ELISA Kit | TNNI1 elisa kit
Hamster Troponin I Type 1, Slow Skeletal (TNNI1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008]
Uniprot Description
TNNI1: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Belongs to the troponin I family.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1q31.3
Cellular Component: cytosol; troponin complex
Molecular Function: actin binding; metal ion binding; protein binding
Biological Process: cardiac muscle contraction; muscle filament sliding; regulation of striated muscle contraction; skeletal muscle contraction; transition between fast and slow fiber; ventricular cardiac muscle morphogenesis
Research Articles on TNNI1
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Product Notes
The Hamster TNNI1 tnni1 (Catalog #AAA9367609) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9367609 ELISA Kit recognizes Hamster TNNI1. It is sometimes possible for the material contained within the vial of "Troponin I Type 1, Slow Skeletal (TNNI1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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