Hamster Dynein Intermediate Chain 1, Axonemal (DNAI1) ELISA Kit | DNAI1 elisa kit
Hamster Dynein Intermediate Chain 1, Axonemal (DNAI1) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
DNAI1: Part of the dynein complex of respiratory cilia. Defects in DNAI1 are the cause of primary ciliary dyskinesia type 1 (CILD1). CILD1 is an autosomal recessive disorder characterized by axonemal abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit situs inversus, due to dysfunction of monocilia at the embryonic node and randomization of left-right body asymmetry. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Defects in DNAI1 are the cause of Kartagener syndrome (KTGS). KTGS is an autosomal recessive disorder characterized by the association of primary ciliary dyskinesia with situs inversus. Clinical features include recurrent respiratory infections, bronchiectasis, infertility, and lateral transposition of the viscera of the thorax and abdomen. The situs inversus is most often total, although it can be partial in some cases (isolated dextrocardia or isolated transposition of abdominal viscera). Belongs to the dynein intermediate chain family.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal
Cellular Component: cilium; cytoplasm; dynein complex; microtubule
Molecular Function: motor activity; protein binding
Biological Process: determination of left/right symmetry; heart development; sperm motility
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Product Notes
The Hamster DNAI1 dnai1 (Catalog #AAA9359813) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9359813 ELISA Kit recognizes Hamster DNAI1. It is sometimes possible for the material contained within the vial of "Dynein Intermediate Chain 1, Axonemal (DNAI1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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