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PHYH2 Blocking Peptide | HACL1 blocking peptide

PHYH2 Antibody (C-term) Blocking Peptide

Gene Names
HACL1; HPCL; HPCL2; PHYH2; 2-HPCL
Synonyms
PHYH2; PHYH2 Antibody (C-term) Blocking Peptide; 2-hydroxyacyl-CoA lyase 1; 41--; 2-hydroxyphytanoyl-CoA lyase; 2-HPCL; Phytanoyl-CoA 2-hydroxylase 2; HACL1; HPCL; HPCL2; HACL1 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human PHYH2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
578
Cellular Location
Peroxisome.
Tissue Location
Expressed in high levels in liver, also expressed in kidney, heart and skeletal muscle
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for HACL1 blocking peptide
Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
54,724 Da
NCBI Official Full Name
2-hydroxyacyl-CoA lyase 1
NCBI Official Synonym Full Names
2-hydroxyacyl-CoA lyase 1
NCBI Official Symbol
HACL1
NCBI Official Synonym Symbols
HPCL; HPCL2; PHYH2; 2-HPCL
NCBI Protein Information
2-hydroxyacyl-CoA lyase 1
UniProt Protein Name
2-hydroxyacyl-CoA lyase 1
UniProt Gene Name
HACL1
UniProt Synonym Gene Names
HPCL; HPCL2; PHYH2; 2-HPCL
UniProt Entry Name
HACL1_HUMAN

Uniprot Description

HACL1: Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. Belongs to the TPP enzyme family.

Protein type: Lyase; EC 4.1.-.-

Chromosomal Location of Human Ortholog: 3p25.1

Cellular Component: peroxisomal matrix; peroxisome

Molecular Function: carbon-carbon lyase activity; cofactor binding; identical protein binding; protein binding; receptor binding; thiamin pyrophosphate binding

Biological Process: fatty acid alpha-oxidation; protein oligomerization

Research Articles on HACL1

Similar Products

Product Notes

The HACL1 hacl1 (Catalog #AAA9227806) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PHYH2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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