Hemagglutinin Influenza A-Vietnam 1203-2004-H5N1 Recombinant Protein | HA H5N1 recombinant protein

Hemagglutinin Influenza A-Vietnam 1203-2004-H5N1 Recombinant

Cat. Num. AAA553127

• Purity: >90%, as determined by SDS-PAGE and HPLC
• Synonyms: Hemagglutinin Influenza A-Vietnam 1203-2004-H5N1; Hemagglutinin Influenza A-Vietnam 1203-2004-H5N1 Recombinant; influenza; h5n1; hemagglutinin; HA H5N1 recombinant protein

• Host: Insect Cells
• Purity/Purification: >90%, as determined by SDS-PAGE and HPLC
• Form/Format: Lyophilized from PBS pH7.4, 5% trehalose,5% mannitol
• Sequence Length: 568

• Domain: Hemagglutinin
• Host Note: DNA sequence encoding Influenza A Virus Hemagglutinin H5N1 subtype Vietnam 1203/2004 strain (Asp17-Gln531), was expressed in Insect cells.
• Reconstitution: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers
• Molecular Weight Note: Recombinant Influenza H5N1 Hemagglutinin is a disulfide-linked monomer protein, and migrates due to glycosylation as an approximately 70 kDa protein under non-reducing conditions and as 45kDa and 25kDa fragments under reducing conditions in SDS-PAGE.
• Preparation and Storage: The lyophilized protein is stable for at least 2 years from date of receipt at -20 degree C.; Upon reconstitution, this product can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months, with a carrier protein without detectable loss of activity. ; ; Avoid repeated freeze/thaw cycles.

Related Product Information for HA H5N1 recombinant protein

Influenza A virus subtype H5N1 is a subtype of the Influenza A virus. Subtype H5N1 is commonly known as avian influenzaor bird flu. H5N1 may cause more than one influenza pandemicas it is expected to continue mutating in birds. The dominant strain of HPAI A (H5N1) evolvedcreating the Z genotype. It has also been called Asian lineage HPAI/A/H5N1 which is divided into 2 antigenicclades. "Clade 1 includes human and bird isolates from Vietnam, Thailand, and Cambodiaand bird isolates from Laosand Malaysia. Clade 2 viruses were first identified in bird isolates from China, Indonesia, Japan, and South Koreabefore spreading westward to the Middle East, Europe, and Africa.

Product Categories/Family for HA H5N1 recombinant protein

Viral Antigens

References

• pathology of highly pathogenic avian influenza virus (H5N1) infection in canada geese (branta canadensis) : preliminary studies .Vet. Pathol., Sep 2009; 46: 966 - 970.
• host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza a virus in mice .J. Virol., Oct 2009; 83: 10417 - 10426.
• in vitro generation of neuraminidase inhibitor resistance in a (H5N1) influenza viruses .Antimicrob. Agents Chemother., Oct 2009; 53: 4433 - 4440.
• detection of mammalian virulence determinants in highly pathogenic avian influenza H5N1 viruses: multivariate analysis of published data .J. Virol., Oct 2009; 83: 9901 - 9910.
• intracellular metabolism of favipiravir (t-705) in uninfected and influenza a (H5N1) virus-infected cells .J. Antimicrob. Chemother., Oct 2009; 64: 741 - 746.