H-2 class II histocompatibility antigen, E-U alpha chain Recombinant Protein | H2-Ea-ps recombinant protein

Recombinant Mouse H-2 class II histocompatibility antigen, E-U alpha chain, partial

Cat. Num. AAA1140446

• Gene Names: H2-Ea-ps; Ia3; Ia-3; H-2Ea; H2-Ea; AI323765; I-Ealpha; E-alpha-f; MHC-H2-Ea
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: H-2 class II histocompatibility antigen; E-U alpha chain; Recombinant Mouse H-2 class II histocompatibility antigen; partial; H2-Ea-ps recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 26-217
• Sequence: IKEEH TIIQAEFYLL PDKRGEYMFD FDGDEIFHVD IEKSETIWRL EEFAKFASFE AQGALANIAV DKANLDVMKK RSNNTPDANV APEVTVLSRS PVNLGEPNIL VCFIDKFSPP VVNVTWLRNG QPVTEGVSET VFLPRDDHLF RKFHYLTFLP STDDFYDCEV DHWGLEEPLR KHWEFEEKTL LPETKEN
• Sequence Length: 192

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 31982789
• NCBI GeneID: 100504404
• NCBI Accession #: NP_034511.2
• NCBI GenBank Nucleotide #: NM_010381.2
• UniProt Accession #: P14439; Q31092; P01904; P04224
• Molecular Weight: 29,108 Da
• NCBI Official Full Name: histocompatibility 2, class II antigen E alpha
• NCBI Official Synonym Full Names: histocompatibility 2, class II antigen E alpha, pseudogene
• NCBI Official Symbol: H2-Ea-ps
• NCBI Official Synonym Symbols: Ia3; Ia-3; H-2Ea; H2-Ea; AI323765; I-Ealpha; E-alpha-f; MHC-H2-Ea
• NCBI Protein Information: histocompatibility 2, class II antigen E alpha
• UniProt Protein Name: H-2 class II histocompatibility antigen, E-U alpha chain
• Protein Family: H-2 class II histocompatibility antigen
• UniProt Gene Name: H2-Ea
• UniProt Synonym Gene Names: H2-Ea-ps

NCBI Description

This locus belongs to the class II major histocompatibility complex (MHC) family of genes, which encode immune response (Ia) antigens that function in the T-cell-dependent immune response. This family member has multiple haplotypes, some of which result in the production of an E-alpha subunit that combines with an E-beta subunit to form a functional E complex at the cell surface. Other haplotypes, including that of the reference genome allele, contain mutations and they thus represent polymorphic pseudogenes that do not produce functional products. These mutations include frameshifting indels, nonsense mutations, and deletions of larger regions. The reference genome haplotype contains a deletion at the 5' end of the gene, including the core promoter region and the transcription start site, and therefore no transcripts result from this haplotype. [provided by RefSeq, Aug 2011]