Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

SDS-Page (Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.)

H11 (HSP22) Recombinant Protein | H11 recombinant protein

H11 (HSP22) Protein

Applications
Western Blot
Synonyms
H11 (HSP22); H11 (HSP22) Protein; HSP22; CRYAC; CMT2L; DHMN2; E2IG1; HSPB8; HMN2; HMN2A; PP1629; H11 recombinant protein
Ordering
For Research Use Only!
Host
Sf9 insect cells
Form/Format
Recombinant protein stored in 50mM Tris-HCl, pH7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Applicable Applications for H11 recombinant protein
Western Blot (WB)
Tag
GST
Species
Human
Preparation and Storage
Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

SDS-Page

(Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.)

SDS-Page (Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.)
Related Product Information for H11 recombinant protein
Full-length recombinant human H11 (HSP22) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. This gene accession number is NM_014365.
H11 or heat shock 22kDa protein 8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of H11 is induced by estrogen in estrogen receptor-positive breast cancer cells, and H11 also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. H11 is involved in regulation of cell proliferation, apoptosis, and carcinogenesis (1). H11 also causes motor neuron-specific neurite degeneration (2).
References
1. Benndorf, R.et.al: Shocking degeneration. Nature Genet. 36: 547-548, 2004.
2. Irobi, J.et.al: Mutant HSPB8 causes motor neuron-specific neurite degeneration. Hum. Molec. Genet. 19: 3254-3265, 2010.

NCBI and Uniprot Product Information

NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
~50kDa

Similar Products

Product Notes

The H11 (Catalog #AAA517048) is a Recombinant Protein produced from Sf9 insect cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's H11 (HSP22) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the H11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "H11 (HSP22), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.