H-89 PKA, Inhibitor | H-89PKA, inhibitor

H-89 PKA Inhibitor

Purity

99% (TLC: 10% Methanol/methylene chloride; Rf = 0.65)

Synonyms

H-89 PKA; H-89 PKA Inhibitor; N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide-2HCl; H-89PKA; inhibitor

Ordering
Cat. Num. AAA8579815 For Research Use Only!

Purity/Purification

99% (TLC: 10% Methanol/methylene chloride; Rf = 0.65)

Form/Format

Off-white solid (m.p. 141-143 degree C)

Molecular Formula

C20H20BrN3O2S-2HCl

CAS Number

27243-85-0

Solubility

Soluble in DMSO: 10mg/ml, 0.1ml

Preparation and Storage

Store solutions at -20 degree C for up to 1 year.

Related Product Information for H-89PKA, inhibitor

Potent, selective and widely used inhibitor of PKA (Ki = 48nM). Cell permeable. Concentration range for cultured cells 30-100uM: osteoblastic cells, renal proximal tubule cells and Xenopus oocytes.

Product Categories/Family for H-89PKA, inhibitor

Compound

References

1: T.Chijiwa et al. J.Biol.Chem. 1990 265 5267
2: M.Muroi and T. Suzuki Cell Signal 1993 5 289
3: M.Fujihara et al. J.Biol.Chem. 1993 268 14898
4: A. Azarani et al. J.Biol.Chem. 1995 270 23166
5: A. Azarani et al. J.Biol.Chem. 1995 270 20004
6: A. Azarani et al. J.Biol.Chem. 1995 270 17898
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.

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H-89 dihydrochloride Biochemical

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N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline Sulfonamide, Dihydrochloride Inhibitor

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Product Notes

The H-89PKA (Catalog #AAA8579815) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "H-89 PKA, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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H-89 PKA, Inhibitor | H-89PKA, inhibitor