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Granzyme D/GZMD Recombinant Protein | GZMD recombinant protein

Recombinant Mouse Granzyme D/GZMD Protein (C-6His)

Gene Names
Gzmd; CCP5; Ctla5; Ctla-5
Purity
>90% as determined by reducing SDS-PAGE.
Synonyms
Granzyme D/GZMD; Recombinant Mouse Granzyme D/GZMD Protein (C-6His); Granzyme D; Gzmd; GZMD recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
>90% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM HEPES, 150mM NaCl, pH 7.4.
Sequence Positions
Ile21-Leu252
Sequence Length
252
Species
Mouse
Endotoxin
<1.0 EU per mug as determined by LAL test.
Fusion Tag
C-6His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for GZMD recombinant protein
Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, but the function of granzyme D is unknown. Previous studies reported that granzyme D is developmentally regulated during pregnancy together with granzymes E, F, and G in granulated metrial gland cells and is upregulated by IL-2 and IL-15. Granzyme D was also suggested to have a role in stromal cell-lymphocyte interactions.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 26.8 kDa
Actual Protein Molecular Mass: 80-90 kDa
NCBI Official Full Name
granzyme D
NCBI Official Synonym Full Names
granzyme D
NCBI Official Symbol
Gzmd
NCBI Official Synonym Symbols
CCP5; Ctla5; Ctla-5
NCBI Protein Information
granzyme D
UniProt Protein Name
Granzyme D
Protein Family
UniProt Gene Name
Gzmd

Uniprot Description

This enzyme is probably necessary for target cell lysis in cell-mediated immune responses.

Research Articles on GZMD

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Product Notes

The GZMD gzmd (Catalog #AAA2553512) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Ile21-Leu252. It is sometimes possible for the material contained within the vial of "Granzyme D/GZMD, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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