Guinea Pig Ubiquitin-conjugating enzyme E2 variant 2 (UBE2V2) ELISA Kit | UBE2V2 elisa kit

Guinea pig Ubiquitin-conjugating enzyme E2 variant 2 (UBE2V2) ELISA Kit

Cat. Num. AAA7243611

• Gene Names: UBE2V2; MMS2; UEV2; EDPF1; UEV-2; DDVIT1; EDAF-1; EDPF-1; DDVit-1
• Reactivity: Guinea Pig
• Synonyms: Ubiquitin-conjugating enzyme E2 variant 2 (UBE2V2); Guinea pig Ubiquitin-conjugating enzyme E2 variant 2 (UBE2V2) ELISA Kit; UBE2V2 elisa kit

• Reactivity: Guinea Pig

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Preparation and Storage: Store all reagents at 2-8 degree C.

Product Categories/Family for UBE2V2 elisa kit

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 4507797
• NCBI GeneID: 7336
• NCBI Accession #: NP_003341.1
• NCBI GenBank Nucleotide #: NM_003350.2
• Molecular Weight: 16,363 Da
• NCBI Official Full Name: ubiquitin-conjugating enzyme E2 variant 2
• NCBI Official Synonym Full Names: ubiquitin-conjugating enzyme E2 variant 2
• NCBI Official Symbol: UBE2V2
• NCBI Official Synonym Symbols: MMS2; UEV2; EDPF1; UEV-2; DDVIT1; EDAF-1; EDPF-1; DDVit-1
• NCBI Protein Information: ubiquitin-conjugating enzyme E2 variant 2; DDVit 1; MMS2 homolog; vitamin D3-inducible protein; 1 alpha,25-dihydroxyvitamin D3-inducible; enterocyte differentiation promoting factor; enterocyte differentiation-promoting factor 1; enterocyte differentiation-associated factor 1; enterocyte differentiation-associated factor EDAF-1; methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of
• UniProt Protein Name: Ubiquitin-conjugating enzyme E2 variant 2
• Protein Family: Ubiquitin-conjugating enzyme
• UniProt Gene Name: UBE2V2
• UniProt Synonym Gene Names: MMS2; UEV2; EDAF-1; EDPF-1
• UniProt Entry Name: UB2V2_HUMAN

NCBI Description

Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes. [provided by RefSeq, Jul 2008]

Uniprot Description

UBE2V2: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Belongs to the ubiquitin-conjugating enzyme family.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 8q11.21

Cellular Component: cytoplasm; nucleus; UBC13-MMS2 complex

Molecular Function: protein binding; small conjugating protein ligase activity; ubiquitin protein ligase binding

Biological Process: regulation of DNA repair; cell proliferation; positive regulation of synaptogenesis; protein polyubiquitination; positive regulation of DNA repair; postreplication repair; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; DNA double-strand break processing; protein ubiquitination; negative regulation of neuron apoptosis