Guinea Pig Phospholipase A2, Lipoprotein Associated (Lp-PL-A2) ELISA Kit | Lp-PL-A2 elisa kit

Guinea pig Phospholipase A2, Lipoprotein Associated (Lp-PL-A2) ELISA Kit

Gene Names

PLA2G2A; MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2

Reactivity

Guinea Pig

Synonyms

Phospholipase A2; Lipoprotein Associated (Lp-PL-A2); Guinea pig Phospholipase A2; Lipoprotein Associated (Lp-PL-A2) ELISA Kit; Lp-PL-A2 elisa kit

Ordering
Cat. Num. AAA269830 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Guinea Pig

Sequence Length

144

Preparation and Storage

Store all reagents at 2-8 degree C.

NCBI and Uniprot Product Information

NCBI GI #

239915991

NCBI GeneID

5320

NCBI Accession #

NP_001155201.1

NCBI GenBank Nucleotide #

NM_001161729.1

Molecular Weight

16,083 Da

NCBI Official Full Name

phospholipase A2, membrane associated

NCBI Official Synonym Full Names

phospholipase A2, group IIA (platelets, synovial fluid)

NCBI Official Symbol

PLA2G2A

NCBI Official Synonym Symbols

MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2

NCBI Protein Information

phospholipase A2, membrane associated; NPS-PLA2; GIIC sPLA2; group IIA phospholipase A2; phosphatidylcholine 2-acylhydrolase 2A; non-pancreatic secretory phospholipase A2

UniProt Protein Name

Phospholipase A2, membrane associated

UniProt Gene Name

PLA2G2A

UniProt Synonym Gene Names

PLA2B; PLA2L; RASF-A; NPS-PLA2

UniProt Entry Name

PA2GA_HUMAN

NCBI Description

The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]

Uniprot Description

PLA2G2A: Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Belongs to the phospholipase A2 family.

Protein type: Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Secreted; Lipid Metabolism - arachidonic acid; EC 3.1.1.4; Secreted, signal peptide; Phospholipase; Endoplasmic reticulum; Mitochondrial; Lipid Metabolism - linoleic acid; Vesicle

Chromosomal Location of Human Ortholog: 1p35

Cellular Component: extracellular space; endoplasmic reticulum membrane; mitochondrion; endoplasmic reticulum; extracellular region; secretory granule

Molecular Function: phospholipase A2 activity; calcium-dependent phospholipase A2 activity; phospholipid binding; calcium ion binding

Biological Process: defense response to Gram-positive bacterium; somatic stem cell maintenance; phosphatidic acid metabolic process; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; lipid catabolic process; negative regulation of epithelial cell proliferation; positive regulation of inflammatory response

Disease: Colorectal Cancer

Research Articles on Lp-PL-A2

1. Increased serum levels of serum amyloid a, PLA2G2, and C reactive protein were observed in patients with benign prostate hyperplasia, localized and metastasized prostate cancer in comparison to healthy individuals.

Similar Products

Product Notes

The Guinea Pig Lp-PL-A2 pla2g2a (Catalog #AAA269830) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA269830 ELISA Kit recognizes Guinea Pig Lp-PL-A2. It is sometimes possible for the material contained within the vial of "Phospholipase A2, Lipoprotein Associated (Lp-PL-A2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Loading...

Guinea Pig Phospholipase A2, Lipoprotein Associated (Lp-PL-A2) ELISA Kit | Lp-PL-A2 elisa kit