Guinea Pig Centrosomal protein of 120 kDa (CEP120) ELISA Kit | CEP120 elisa kit
Guinea pig Centrosomal protein of 120 kDa (CEP120) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Uniprot Description
CEP120: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis. Belongs to the CEP120 family. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 5q23.2
Cellular Component: centrosome; cytoplasm
Molecular Function: protein C-terminus binding
Biological Process: regulation of microtubule-based process; astral microtubule organization and biogenesis; regulation of protein localization; neurogenesis; cerebral cortex development; interkinetic nuclear migration
Disease: Short-rib Thoracic Dysplasia 13 With Or Without Polydactyly
Research Articles on CEP120
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Product Notes
The Guinea Pig CEP120 cep120 (Catalog #AAA7235767) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7235767 ELISA Kit recognizes Guinea Pig CEP120. It is sometimes possible for the material contained within the vial of "Centrosomal protein of 120 kDa (CEP120), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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