Guinea Pig Bcl-2-like protein 11 (BCL2L11) ELISA Kit | BCL2L11 elisa kit
Guinea pig Bcl-2-like protein 11 (BCL2L11) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
proapototic Bcl-2 related protein that interacts with anti-apoptotic Bcl-2 family members to play a role in regulation of apoptosis [RGD, Feb 2006]
Uniprot Description
BIM: a pro-apoptotic member of the BCL-2 protein family. Interacts with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and act as an apoptotic activator. Its expression can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role in neuronal and lymphocyte apoptosis. Transgenic studies in the mouse suggested that this protein functions as an essential initiator of the apoptosis in thymocyte-negative selection. Nineteen alternatively spliced transcript variants of this gene have been reported.
Protein type: Apoptosis
Cellular Component: microtubule; extrinsic to membrane; intracellular membrane-bound organelle; mitochondrion; cytoplasm; intracellular; cytosol
Molecular Function: protein binding; microtubule binding
Biological Process: positive regulation of apoptosis; cell-matrix adhesion; pigmentation during development; myeloid cell homeostasis; ear development; positive regulation of caspase activity; B cell apoptosis; cellular process regulating host cell cycle in response to virus; positive regulation of apoptosis by virus; post-embryonic development; regulation of apoptosis; mammary gland development; B cell homeostasis; positive regulation of neuron apoptosis; T cell homeostasis; kidney development; post-embryonic organ morphogenesis; leukocyte homeostasis; spleen development; caspase activation; thymus development; in utero embryonic development; positive regulation of protein homooligomerization; male gonad development; positive regulation of cell cycle; lumen formation; regulation of organ growth; odontogenesis of dentine-containing teeth; DNA damage response, signal transduction resulting in induction of apoptosis; spermatogenesis; regulation of pigmentation during development; brain development; lymphocyte homeostasis
Research Articles on BCL2L11
Similar Products
Product Notes
The Guinea Pig BCL2L11 bcl2l11 (Catalog #AAA7240775) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7240775 ELISA Kit recognizes Guinea Pig BCL2L11. It is sometimes possible for the material contained within the vial of "Bcl-2-like protein 11 (BCL2L11), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
