Guinea Pig Apoptosis-stimulating of p53 protein 1 (PPP1R13B) ELISA Kit | PPP1R13B elisa kit
Guinea pig Apoptosis-stimulating of p53 protein 1 (PPP1R13B) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008]
Uniprot Description
PPP1R13B: Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Belongs to the ASPP family.
Protein type: Protein phosphatase, regulatory subunit; Tumor suppressor; Apoptosis
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleus
Molecular Function: protein binding; transcription factor binding
Biological Process: negative regulation of cell cycle
Research Articles on PPP1R13B
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Product Notes
The Guinea Pig PPP1R13B ppp1r13b (Catalog #AAA7237316) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7237316 ELISA Kit recognizes Guinea Pig PPP1R13B. It is sometimes possible for the material contained within the vial of "Apoptosis-stimulating of p53 protein 1 (PPP1R13B), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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