Guinea Pig 40S ribosomal protein S24 (RPS24) ELISA Kit | RPS24 elisa kit
Guinea pig 40S ribosomal protein S24 (RPS24) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S24E family of ribosomal proteins. It is located in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Mutations in this gene result in Diamond-Blackfan anemia. [provided by RefSeq, Nov 2008]
Uniprot Description
RPS24: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits. Defects in RPS24 are the cause of Diamond-Blackfan anemia type 3 (DBA3). DBA3 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Belongs to the ribosomal protein S24e family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Ribosomal; RNA-binding; Translation
Chromosomal Location of Human Ortholog: 10q22
Cellular Component: small ribosomal subunit; membrane; cytoplasm; nucleolus; cytosol; nucleus
Molecular Function: structural constituent of ribosome; translation initiation factor binding; nucleotide binding
Biological Process: SRP-dependent cotranslational protein targeting to membrane; translation; viral reproduction; translational termination; viral infectious cycle; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ribosomal small subunit biogenesis and assembly; erythrocyte homeostasis; cellular protein metabolic process; translational elongation; mRNA catabolic process, nonsense-mediated decay; translational initiation; gene expression; viral transcription; rRNA processing
Disease: Diamond-blackfan Anemia 3
Research Articles on RPS24
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Product Notes
The Guinea Pig RPS24 rps24 (Catalog #AAA7204564) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7204564 ELISA Kit recognizes Guinea Pig RPS24. It is sometimes possible for the material contained within the vial of "40S ribosomal protein S24 (RPS24), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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