Guinea Pig 26S proteasome non-ATPase regulatory subunit 7 (PSMD7) ELISA Kit | PSMD7 elisa kit

Guinea pig 26S proteasome non-ATPase regulatory subunit 7 (PSMD7) ELISA Kit

Cat. Num. AAA7228360

• Gene Names: PSMD7; P40; S12; Rpn8; MOV34
• Reactivity: Guinea Pig
• Synonyms: 26S proteasome non-ATPase regulatory subunit 7 (PSMD7); Guinea pig 26S proteasome non-ATPase regulatory subunit 7 (PSMD7) ELISA Kit; PSMD7 elisa kit

• Reactivity: Guinea Pig

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Assay Type: Competitive
• Detection Range: 0.5-10ng/mL
• Sensitivity: 0.1ng/mL
• Preparation and Storage: Store all reagents at 2-8 degree C.

Product Categories/Family for PSMD7 elisa kit

Cell Biology

NCBI and Uniprot Product Information

• NCBI GI #: 25777615
• NCBI GeneID: 5713
• NCBI Accession #: NP_002802.2
• NCBI GenBank Nucleotide #: NM_002811.4
• Molecular Weight: 37,025 Da
• NCBI Official Full Name: 26S proteasome non-ATPase regulatory subunit 7
• NCBI Official Synonym Full Names: proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
• NCBI Official Symbol: PSMD7
• NCBI Official Synonym Symbols: P40; S12; Rpn8; MOV34
• NCBI Protein Information: 26S proteasome non-ATPase regulatory subunit 7; Mov34 homolog; proteasome subunit p40; 26S proteasome regulatory subunit S12; 26S proteasome regulatory subunit rpn8; Moloney leukemia virus-34 proviral integration; proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)
• UniProt Protein Name: 26S proteasome non-ATPase regulatory subunit 7
• Protein Family: 26S proteasome non-ATPase regulatory
• UniProt Gene Name: PSMD7
• UniProt Synonym Gene Names: MOV34L
• UniProt Entry Name: PSMD7_HUMAN

NCBI Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008]

Uniprot Description

PSMD7: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Belongs to the peptidase M67A family.

Protein type: Proteasome complex; Protease

Chromosomal Location of Human Ortholog: 16q22.3

Cellular Component: proteasome complex; nucleoplasm; membrane; proteasome regulatory particle; nucleus; cytosol

Molecular Function: protein binding; protein homodimerization activity

Biological Process: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; protein polyubiquitination; viral reproduction; apoptosis; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of apoptosis; antigen processing and presentation of peptide antigen via MHC class I; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; gene expression; mitotic cell cycle; regulation of amino acid metabolic process; G1/S transition of mitotic cell cycle; negative regulation of apoptosis