Translation factor GUF1, mitochondrial (GUF1) Recombinant Protein | GUF1 recombinant protein
Recombinant Human Translation factor GUF1, mitochondrial (GUF1)
Gene Names
GUF1; EF4; EF-4; EIEE40
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Translation factor GUF1; mitochondrial (GUF1); Recombinant Human Translation factor GUF1; GUF1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
50-669, Full length protein
Sequence
SSAEFKEKLDMSRFPVENIRNFSIVAHVDHGKSTLADRLLELTGTIDKTKNNKQVLDKLQVERERGITVKAQTASLFYNCEGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIPVINKIDLKNADPERVENQIEKVFDIPSDECIKISAKLGTNVESVLQAIIERIPPPKVHRKNPLRALVFDSTFDQYRGVIANVALFDGVVSKGDKIVSAHTQKTYEVNEVGVLNPNEQPTHKLYAGQVGYLIAGMKDVTEAQIGDTLCLHKQPVEPLPGFKSAKPMVFAGMYPLDQSEYNNLKSAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSSKLIKEHREKEITIINPAQFPDKSKVTEYLEPVVLGTIITPDEYTGKIMMLCEARRAVQKNMIFIDQNRVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTAELVKMDILLNGNTVEELVTVVHKDKAHSIGKAICERLKDSLPRQLFEIAIQAAIGSKIIARETVKAYRKNVLAKCYGGDITRKMKLLKRQAEGKKKLRKIGNVEVPKDAFIKVLKTQSSK
Sequence Length
620
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74,328 Da
NCBI Official Full Name
translation factor GUF1, mitochondrial isoform 1
NCBI Official Synonym Full Names
GUF1 homolog, GTPase
NCBI Official Symbol
GUF1
NCBI Official Synonym Symbols
EF4; EF-4; EIEE40
NCBI Protein Information
translation factor GUF1, mitochondrial
UniProt Protein Name
Translation factor GUF1, mitochondrial
Protein Family
UniProt Gene Name
GUF1
UniProt Synonym Gene Names
EF-4
NCBI Description
This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Uniprot Description
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
Research Articles on GUF1
Similar Products
Product Notes
The GUF1 guf1 (Catalog #AAA1485971) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 50-669, Full length protein. The amino acid sequence is listed below: SSAEFKEKLD MSRFPVENIR NFSIVAHVDH GKSTLADRLL ELTGTIDKTK NNKQVLDKLQ VERERGITVK AQTASLFYNC EGKQYLLNLI DTPGHVDFSY EVSRSLSACQ GVLLVVDANE GIQAQTVANF FLAFEAQLSV IPVINKIDLK NADPERVENQ IEKVFDIPSD ECIKISAKLG TNVESVLQAI IERIPPPKVH RKNPLRALVF DSTFDQYRGV IANVALFDGV VSKGDKIVSA HTQKTYEVNE VGVLNPNEQP THKLYAGQVG YLIAGMKDVT EAQIGDTLCL HKQPVEPLPG FKSAKPMVFA GMYPLDQSEY NNLKSAIEKL TLNDSSVTVH RDSSLALGAG WRLGFLGLLH MEVFNQRLEQ EYNASVILTT PTVPYKAVLS SSKLIKEHRE KEITIINPAQ FPDKSKVTEY LEPVVLGTII TPDEYTGKIM MLCEARRAVQ KNMIFIDQNR VMLKYLFPLN EIVVDFYDSL KSLSSGYASF DYEDAGYQTA ELVKMDILLN GNTVEELVTV VHKDKAHSIG KAICERLKDS LPRQLFEIAI QAAIGSKIIA RETVKAYRKN VLAKCYGGDI TRKMKLLKRQ AEGKKKLRKI GNVEVPKDAF IKVLKTQSSK. It is sometimes possible for the material contained within the vial of "Translation factor GUF1, mitochondrial (GUF1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
