Human germ cell associated 2 (haspin) ELISA Kit | GSG2 elisa kit

Human Serine/threonine-protein kinase haspin, GSG2 ELISA Kit

Cat. Num. AAA9332777

• Gene Names: GSG2; HASPIN
• Reactivity: Human
• Synonyms: germ cell associated 2 (haspin); Human Serine/threonine-protein kinase haspin; GSG2 ELISA Kit; Human Serine/threonine-protein kinase haspin (GSG2) ELISA kit; HASPIN; germ cell-specific gene 2; haploid germ cell-specific nuclear protein kinase; haspin; GSG2 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Serum, Plasma and Tissue Homogenate
• Assay Type: Sandwich
• Detection Range: 0.25ng/ml-8ng/ml.
• Sensitivity: 0.1ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for GSG2 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of GSG2 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

NCBI and Uniprot Product Information

• NCBI GI #: 56790919
• NCBI GeneID: 83903
• NCBI Accession #: NP_114171.2
• NCBI GenBank Nucleotide #: NM_031965.2
• UniProt Accession #: Q8TF76; Q5U5K3; Q96MN1; Q9BXS7
• Molecular Weight: 88,495 Da
• NCBI Official Full Name: serine/threonine-protein kinase haspin
• NCBI Official Synonym Full Names: germ cell associated 2 (haspin)
• NCBI Official Symbol: GSG2
• NCBI Official Synonym Symbols: HASPIN
• NCBI Protein Information: serine/threonine-protein kinase haspin; H-haspin; germ cell-specific gene 2 protein; haploid germ cell-specific nuclear protein kinase
• UniProt Protein Name: Serine/threonine-protein kinase haspin
• Protein Family: Serine/threonine-protein kinase haspin
• UniProt Gene Name: GSG2
• UniProt Entry Name: HASP_HUMAN

Uniprot Description

Haspin: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Haspin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, Other; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Other group; Haspin family

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: centrosome; cytoplasm; spindle; chromosome; nucleus

Molecular Function: protein binding; DNA binding; ATP binding; protein kinase activity

Biological Process: mitotic sister chromatid cohesion; protein amino acid phosphorylation