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Typical Testing Data/Standard Curve (for reference only) (Fig.1. Human Proteinase 3 (PR3) Standard Curve.)

Human Proteinase 3 (PR3) ELISA Kit | PR3 elisa kit

Human Proteinase 3 (PR3) ELISA Kit

Gene Names
PRTN3; MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA
Reactivity
Human
Synonyms
Proteinase 3 (PR3); Human Proteinase 3 (PR3) ELISA Kit; PRTN3; ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP4; P29; PR-3; PR3; Wegener granulomatosis autoantigen; azurophil granule protein 7; leukocyte proteinase 3; myeloblastin; serine proteinase; neutrophil; PR3 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
256
Assay Type
Sandwich
Preparation and Storage
Store at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

(Fig.1. Human Proteinase 3 (PR3) Standard Curve.)

Typical Testing Data/Standard Curve (for reference only) (Fig.1. Human Proteinase 3 (PR3) Standard Curve.)
Related Product Information for PR3 elisa kit
Principle of the Assay: Human Proteinase 3 (PR3) ELISA Kit employs a two-site sandwich ELISA to quantitate PR3 in samples. An antibody specific for Human PR3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PR3 present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugated PR3 detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of PR3 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
myeloblastin
NCBI Official Synonym Full Names
proteinase 3
NCBI Official Symbol
PRTN3
NCBI Official Synonym Symbols
MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA
NCBI Protein Information
myeloblastin
UniProt Protein Name
Myeloblastin
UniProt Gene Name
PRTN3
UniProt Synonym Gene Names
MBN; PR-3; PR3; NP-4
UniProt Entry Name
PRTN3_HUMAN

Uniprot Description

PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily.

Protein type: Protease; Cell cycle regulation; EC 3.4.21.76

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: extracellular matrix; extracellular space; plasma membrane; cytosol

Molecular Function: enzyme binding; serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: negative regulation of phagocytosis; collagen catabolic process; positive regulation of cell proliferation; blood coagulation; proteolysis

Research Articles on PR3

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Product Notes

The Human PR3 prtn3 (Catalog #AAA9715999) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9715999 ELISA Kit recognizes Human PR3. It is sometimes possible for the material contained within the vial of "Proteinase 3 (PR3), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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