Mouse Gastrin-reliasing peptide ELISA Kit | GRP elisa kit
Mouse Gastrin-reliasing peptide ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Uniprot Description
GRP: GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP- receptor gene expression, long-term potentiation, and amygdala- dependent memory for fear. Belongs to the bombesin/neuromedin-B/ranatensin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 18q21.1-q21.32
Cellular Component: extracellular space; extracellular region
Molecular Function: neuropeptide hormone activity; receptor binding
Biological Process: neuropeptide signaling pathway; signal transduction
Research Articles on GRP
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Product Notes
The Mouse GRP grp (Catalog #AAA732741) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA732741 ELISA Kit recognizes Mouse GRP. It is sometimes possible for the material contained within the vial of "Gastrin-reliasing peptide, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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