Human glutamate receptor, ionotropic, N-methyl-D-aspartate 3A ELISA Kit | GRIN3A elisa kit
Human Glutamate [NMDA] receptor subunit 3A, GRIN3A ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity. [provided by RefSeq, Jul 2008]
Uniprot Description
NMDAR3A: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. May play a role in the development of dendritic spines. May play a role in PPP2CB-NMDAR mediated signaling mechanism. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3A/GRIN3A subfamily.
Protein type: Membrane protein, integral; Channel, ligand-gated; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 9q31.1
Cellular Component: postsynaptic membrane; neuron projection; cell soma; membrane; dendrite; postsynaptic density; integral to membrane; synapse; cell junction; N-methyl-D-aspartate selective glutamate receptor complex
Molecular Function: identical protein binding; neurotransmitter binding; protein binding; extracellular-glutamate-gated ion channel activity; protein phosphatase 2A binding; N-methyl-D-aspartate selective glutamate receptor activity; calcium channel activity; glycine binding
Biological Process: synaptic transmission, glutamatergic; response to ethanol; prepulse inhibition; ionotropic glutamate receptor signaling pathway; calcium ion transport; rhythmic process; dendrite development
Research Articles on GRIN3A
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Product Notes
The Human GRIN3A grin3a (Catalog #AAA9337285) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337285 ELISA Kit recognizes Human GRIN3A. It is sometimes possible for the material contained within the vial of "glutamate receptor, ionotropic, N-methyl-D-aspartate 3A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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