Mouse grainyhead-like 2 (Drosophila) ELISA Kit | GRHL2 elisa kit
Mouse Grainyhead-like protein 2 homolog, GRHL2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
GRHL2: May function as a transcription factor. Defects in GRHL2 are the cause of deafness autosomal dominant type 28 (DFNA28). DFNA28 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. DFNA28 is characterized by mild to moderate hearing loss across most frequencies that progressed to severe loss in the higher frequencies by the fifth decade. Age at onset varied, with the earliest case documented at 7 years of age. Belongs to the grh/CP2 family. Grainyhead subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor
Cellular Component: membrane; intercellular junction; nucleus
Molecular Function: DNA binding; chromatin DNA binding; sequence-specific DNA binding; transcription factor activity
Biological Process: neural tube development; epidermis development; camera-type eye development; transcription, DNA-dependent; in utero embryonic development; respiratory tube development; multicellular organism growth; negative regulation of keratinocyte differentiation; embryonic cranial skeleton morphogenesis; positive regulation of telomerase activity; regulation of transcription from RNA polymerase II promoter; cell proliferation; regulation of transcription, DNA-dependent; regulation of gene expression; neural tube closure; embryonic organ development; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; brain development; cell adhesion
Research Articles on GRHL2
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Product Notes
The Mouse GRHL2 grhl2 (Catalog #AAA9321795) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9321795 ELISA Kit recognizes Mouse GRHL2. It is sometimes possible for the material contained within the vial of "grainyhead-like 2 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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