Putative gustatory receptor 66a (Gr66a) Recombinant Protein | Gr66a recombinant protein

Recombinant Drosophila melanogaster Putative gustatory receptor 66a (Gr66a), partial

• Gene Names: Gr66a; CG7189; DmelCG7189; Gr66; Gr66A; GR66a; GR66A; Gr66C1; GR66C1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Putative gustatory receptor 66a (Gr66a); Recombinant Drosophila melanogaster Putative gustatory receptor 66a (Gr66a); partial; Gr66a recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 527

• Species: Drosophila melanogaster (Fruit fly)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 281365837
• NCBI GeneID: 38935
• NCBI Accession #: NP_523971.3
• NCBI GenBank Nucleotide #: NM_079247.3
• UniProt Accession #: Q9VSH2
• Molecular Weight: 59,081 Da
• NCBI Official Full Name: gustatory receptor 66a
• NCBI Official Synonym Full Names: Gustatory receptor 66a
• NCBI Official Symbol: Gr66a
• NCBI Official Synonym Symbols: CG7189; DmelCG7189; Gr66; Gr66A; GR66a; GR66A; Gr66C1; GR66C1
• NCBI Protein Information: CG7189 gene product from transcript CG7189-RB
• UniProt Protein Name: Gustatory receptor for bitter taste 66a
• Protein Family: Gustatory receptor for bitter taste
• UniProt Gene Name: Gr66a

Uniprot Description

Gustatory receptor required for response to the bitter in taste neurons. Gr66a cells respond to bitter compounds such as caffeine, theophylline, threonine or valine. Flies avoid bitter substances, suggesting that Gr66a neuron activity is sufficient to mediate avoidance behavior. Required for sensing and avoiding N,N-Diethyl-meta-toluamide (DEET), the most widely used insect repellent worldwide, as well as to L-canavanine, a plant-derived insecticide. Gr66a neurons are also involved in the sex-specific perception of molecules inducing male avoidance behavior, probably through sensing 7-tricosene (7-T), a male cuticular pheromone and leading to inhibition of male-male courtship. Finally, plays also a role in oviposition behavior, in which females evaluate their environment and choose to lay eggs on substrates they may find aversive in other contexts.