Envelope glycoprotein (GP) Recombinant Protein | PUUVsMgp1 recombinant protein
Recombinant Puumala virus Envelope glycoprotein (GP)
NCBI and Uniprot Product Information
Uniprot Description
Function: Glycoprotein G1 and glycoprotein G2 interact with each other and are present at the surface of the virion. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion. G1 contains an ITAM motif which is likely to dysregulate normal immune and endothelial cell responses and contribute to virus pathogenesis
By similarity.
Subunit structure: G1 and G2 interacts with each other
By similarity.
Subcellular location: Glycoprotein G1: Virion membrane; Single-pass type I membrane protein
Potential. Host Golgi apparatus membrane; Single-pass type I membrane protein
Potential. Host endoplasmic reticulum membrane; Single-pass type I membrane protein
Potential. Note: Interaction between G1 and G2 is essential for proper targeting of G1 to the Golgi complex, where virion budding occurs
By similarity.Glycoprotein G2: Virion membrane; Single-pass type I membrane protein
Potential. Host Golgi apparatus membrane; Single-pass type I membrane protein
Potential.
Post-translational modification: Specific enzymatic cleavages in vivo yield mature proteins including glycoprotein G1 and glycoprotein G2.
Sequence similarities: Belongs to the hantavirus envelope glycoprotein family.Contains 1 ITAM domain.
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Product Notes
The PUUVsMgp1 gp (Catalog #AAA1042848) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 659-1148. The amino acid sequence is listed below: ETQNLNDGWT DTAHGSGIIP MKADLELDFS LPSSASYTYR RQLQNPANEQ EKIPFHLQIS KQVIHAEIQH LGHWMDATFN LKTAFHCYGS CEKYAYPWQT AGCFVEKDYE YETGWGCNPP DCPGVGTGCT ACGVYLDKLK SVGKVFKIVS LRYTRKVCIQ LGTGQTCKTV DSNDCLITTS VKVCLIGTIS KFQPSDTLLF LGPLQQGGLI FKQWCTTTCQ FGDPGDIMST PTGMKCPELN GSFRKKCAFA TTPVCQFDGN TISGYKRMVA TKDSFQSFNV TEPHISTSAL EWIDLDSSLR DHINVIVSRD LSFQDLSETP CQVDLTTSAT DGAWGSGVGF NLVCTVSLTE CSAFLTSIKA CHAAMCYGST TTNLVRGQNT IHVVGKGGHS GSKFMCCHDT KCSSTGLVAA APHLDRVTGF NQADSDKIFD DGAPECGMSC WFKKLGEWVL GVLNGNWMVV AVLIALLILS IFLFALCCPR RPSYKKDHKP. It is sometimes possible for the material contained within the vial of "Envelope glycoprotein (GP), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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