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Envelope glycoprotein (GP) Recombinant Protein | GP recombinant protein

Recombinant Puumala virus Envelope glycoprotein (GP)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Envelope glycoprotein (GP); Recombinant Puumala virus Envelope glycoprotein (GP); GP recombinant protein
Ordering
For Research Use Only!
Host
Cell Free Expression
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
659-1148aa; full length protein
Sequence
ETQNLNAGWTDTAHGSGIIPMKTDLELDFSLPSSASYTYRRQLQNPANEQEKIPFHLQLS KQVIHAEIQHLGHWMDATFNLKTAFHCYGSCEKYAYPWQTAGCFIEKDYEYETGWGCNPP DCPGVGTGCTACGVYLDKLKSVGKVFKIVSLRYTRKVCIQLGTEQTCKTVDSNDCLITTS VKVCLIGTISKFQPSDTLLFLGPLQQGGLIFKQWCTTTCQFGDPGDIMSTPTGMKCPELN GSFRKKCAFATTPVCQFDGNTISGYKRMIATKDSFQSFNVTEPHISTSALEWIDPDSSLR DHINVIVSRDLSFQDLSETPCQIDLATASIDGAWGSGVGFNLVCTVSLTECSAFLTSIKA CDAAMCYGSTTANLVRGQNTIHIVGKGGHSGSKFMCCHDTKCSSTGLVAAAPHLDRVTGY NQADSDKIFDDGAPECGMSCWFKKSGEWILGVLNGNWMVVAVLVVLLILSILLFTLCCPR RPSYRKEHKP
Sequence Length
Full length protein
Application Notes
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Species
Puumala virus (strain K27)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Product Categories/Family for GP recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
126,574 Da
NCBI Official Full Name
Envelopment polyprotein
UniProt Protein Name
Envelopment polyprotein
Protein Family
UniProt Gene Name
GP
UniProt Synonym Gene Names
Gc
UniProt Entry Name
GP_PUUMK

Uniprot Description

Glycoprotein N and glycoprotein C interact with each other and are present at the surface of the virion. They are able to attach the virion to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Also promote fusion of viral membrane with host endosomal membrane after endocytosis of the virion. Glycoprotein N contains an ITAM motif which is likely to dysregulate normal immune and endothelial cell responses and contribute to virus pathogenesis ().

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Product Notes

The GP gp (Catalog #AAA7015953) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 659-1148aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the GP gp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ETQNLNAGWT DTAHGSGIIP MKTDLELDFS LPSSASYTYR RQLQNPANEQ EKIPFHLQLS KQVIHAEIQH LGHWMDATFN LKTAFHCYGS CEKYAYPWQT AGCFIEKDYE YETGWGCNPP DCPGVGTGCT ACGVYLDKLK SVGKVFKIVS LRYTRKVCIQ LGTEQTCKTV DSNDCLITTS VKVCLIGTIS KFQPSDTLLF LGPLQQGGLI FKQWCTTTCQ FGDPGDIMST PTGMKCPELN GSFRKKCAFA TTPVCQFDGN TISGYKRMIA TKDSFQSFNV TEPHISTSAL EWIDPDSSLR DHINVIVSRD LSFQDLSETP CQIDLATASI DGAWGSGVGF NLVCTVSLTE CSAFLTSIKA CDAAMCYGST TANLVRGQNT IHIVGKGGHS GSKFMCCHDT KCSSTGLVAA APHLDRVTGY NQADSDKIFD DGAPECGMSC WFKKSGEWIL GVLNGNWMVV AVLVVLLILS ILLFTLCCPR RPSYRKEHKP. It is sometimes possible for the material contained within the vial of "Envelope glycoprotein (GP), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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