Rat Glycine N-methyltransferase ELISA Kit | Gnmt elisa kit
Rat Glycine N-methyltransferase ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
catalyzes the conversion of S-adenosyl-L-methionine and glycine to S-adenosyl-L-homocysteine and sarcosine; involved in S-adenosylmethionine and folate metabolism [RGD, Feb 2006]
Uniprot Description
GNMT: Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine. Defects in GNMT are the cause of glycine N- methyltransferase deficiency (GNMT deficiency); also known as hypermethioninemia. The only clinical abnormalities in patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases. Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.
Protein type: Methyltransferase; Amino Acid Metabolism - glycine, serine and threonine; EC 2.1.1.20
Cellular Component: cytoplasm; cytosol; nucleus
Molecular Function: folic acid binding; glycine binding; glycine N-methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity
Biological Process: folic acid metabolic process; glycine metabolic process; glycogen metabolic process; methionine metabolic process; methylation; one-carbon compound metabolic process; protein homotetramerization; protein tetramerization; regulation of gluconeogenesis; S-adenosylhomocysteine metabolic process; S-adenosylmethionine metabolic process
Research Articles on Gnmt
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Product Notes
The Rat Gnmt gnmt (Catalog #AAA2886814) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886814 ELISA Kit recognizes Rat Gnmt. It is sometimes possible for the material contained within the vial of "Glycine N-methyltransferase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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